Here's a quick look at what I've played so far in 2010 in the order played:
Muramasa: The Demon Blade (Wii), Mass Effect 2 (Xbox 360), Fallout 3: Broken Steel DLC (Xbox 360)
And the plan from now till as far as I've thought about:
Bayonetta (Xbox 360), Heavy Rain (PS3), Yakuza 2 (PS2), Yakuza 3 (PS3), God of War III (PS3), Red Dead Redemption (Xbox 360), Resident Evil 5 Gold (PS3 or maybe Xbox 360, haven't decided).
Nothing is really for sure beyond Bayonetta and Heavy Rain though. Just thinking out loud.